Evaluation of genotoxicity of the acute gamma radiation on earthworm Eisenia fetida using single cell gel electrophoresis technique (Comet assay)
K Sowmithra, NJ Shetty, SK Jha… - Mutation Research/Genetic …, 2015 - Elsevier
Earthworms (Eisenia fetida) most suitable biological indicators of radioactive pollution.
Radiation-induced lesions in DNA can be considered to be molecular markers for early
effects of ionizing radiation. Gamma radiation produces a wide spectrum of DNA. Some of
these lesions, ie, DNA strand breaks and alkali labile sites can be detected by the single-cell
gel electrophoresis (SCGE) or comet assay by measuring the migration of DNA from
immobilized nuclear DNA. E. fetida were exposed to different doses of gamma radiation, ie …
Radiation-induced lesions in DNA can be considered to be molecular markers for early
effects of ionizing radiation. Gamma radiation produces a wide spectrum of DNA. Some of
these lesions, ie, DNA strand breaks and alkali labile sites can be detected by the single-cell
gel electrophoresis (SCGE) or comet assay by measuring the migration of DNA from
immobilized nuclear DNA. E. fetida were exposed to different doses of gamma radiation, ie …
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