Evaluation of in vivo genotoxicity of cypermethrin in Drosophila melanogaster using the alkaline Comet assay

I Mukhopadhyay, DK Chowdhuri, M Bajpayee… - …, 2004 - academic.oup.com
The single cell gel electrophoresis (SCGE) assay, also known as the Comet assay, is one of
the most promising genotoxicity tests developed in recent years to measure and analyse
DNA damage in single cells. The present study was undertaken to assess the in vivo
genotoxicity of the synthetic pyrethroid cypermethrin in brain ganglia and anterior mid gut of
Drosophila melanogaster. Freshly emerged first instar larvae (22±2 h) were placed in
different concentrations of cypermethrin (0.0004, 0.0008, 0.002, 0.2 and 0.5 ppm) mixed in …

Evaluation of in vivo genotoxicity of cypermethrin in Drosophila melanogaster using the alkaline Comet assay.

IM Indranil Mukhopadhyay, DK Chowdhuri… - 2004 - cabidigitallibrary.org
The single cell gel electrophoresis (SCGE) assay, also known as the Comet assay, is one of
the most promising genotoxicity tests developed in recent years to measure and analyse
DNA damage in single cells. The present study was undertaken to assess the in vivo
genotoxicity of the synthetic pyrethroid cypermethrin in brain ganglia and anterior mid gut of
Drosophila melanogaster. Freshly emerged first instar larvae (22±2 h) were placed in
different concentrations of cypermethrin (0.0004, 0.0008, 0.002, 0.2 and 0.5 ppm) mixed in …
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