the etiological agent of coronavirus disease 2019 (COVID-19), has caused immense global
disruption. With the rapid accumulation of SARS-CoV-2 genome sequences, however,
thousands of genomic variants of SARS-CoV-2 are now publicly available. To improve the
tracing of the viral genomes' evolution during the development of the pandemic, we
analyzed single nucleotide variants (SNVs) in 121,618 high-quality SARS-CoV-2 genomes …