Exercise training reverses the age-related decline in tyrosine hydroxylase expression in rat hypothalamus

N Türner, JS LaRochelle… - The Journals of …, 1997 - academic.oup.com
Tyrosine hydroxylase (TH) is the rate-limiting enzymatic step in the catecholamine
biosynthesis pathway. Some studies have demonstrated that aging is associated with a
decrease in TH activity and TH mRNA in rat hypothalamus. We previously demonstrated that
exercise training can decrease TH gene expression in the adrenal medulla of young but not
senescent rats. This study was designed to examine the effects of endurance training on the
TH expression in hypothalamus with aging. To this end, we assessed TH mRNA, TH …

[引用][C] Exercise Training Reverses the Age-Related Decline in Tyrosine Hydroxylase Expression in Rat...

N Tumer, JS LaRochelle - Journals of Gerontology Series A …, 1997 - search.ebscohost.com
… Some studies have demonstrated that aging is associated with a decrease in TH activity
and TH mRNA in rat hypothalamus. We previously demonstrated that exercise training can
decrease TH gene expression in the adrenal medulla of young but not senescent rats. This
study was designed to examine the effects of endurance training on the TH expression in
hypothalamus with aging. To this end, we assessed …
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