Exercise-induced enhancement of synaptic function triggered by the inverse BAR protein, Mtss1L
Exercise is a potent enhancer of learning and memory, yet we know little of the underlying
mechanisms that likely include alterations in synaptic efficacy in the hippocampus. To
address this issue, we exposed mice to a single episode of voluntary exercise, and
permanently marked activated mature hippocampal dentate granule cells using conditional
Fos-TRAP mice. Exercise-activated neurons (Fos-TRAPed) showed an input-selective
increase in dendritic spines and excitatory postsynaptic currents at 3 days post-exercise …
mechanisms that likely include alterations in synaptic efficacy in the hippocampus. To
address this issue, we exposed mice to a single episode of voluntary exercise, and
permanently marked activated mature hippocampal dentate granule cells using conditional
Fos-TRAP mice. Exercise-activated neurons (Fos-TRAPed) showed an input-selective
increase in dendritic spines and excitatory postsynaptic currents at 3 days post-exercise …
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