Experimental and theoretical studies of a pyrazole-thiazolidin-2, 4-di-one hybrid

M Mushtaque, F Avecilla, A Haque, A Perwez… - Journal of Molecular …, 2017 - Elsevier
The present work describes synthesis, characterization and biological evaluations of a
hybrid compound 10 composed of two intriguing scaffolds pyrazole and thiazolidin-2, 4-di-
one. The title compound was obtained via multi-step reaction and characterized by a
number of techniques (viz. IR, UV–Visible, 1 H-NMR, 13 C-NMR and MS) including X-ray
crystallography. The structural and photophysical data of compound 10 were well supported
by theoretical calculations performed at density functional (DFT) level. In-vitro anticancer …
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