We report an experimental implementation of free-space quantum secure direct communication based on single photons. The quantum communication scheme uses phase encoding, and the asymmetric Mach–Zehnder interferometer is optimized so as to automatically compensate phase drift of the photons during their transitions over the free-space medium. At a 16 MHz pulse repetition frequency, an information transmission rate of 500 bps over a 10 m free space with a mean quantum bit error rate of 0.49%±0.27% is achieved. The security is analyzed under the scenario that Eve performs the collective attack for single-photon state and the photon number splitting attack for multi-photon state in the depolarizing channel. Our results show that quantum secure direct communication is feasible in free space.