Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: an in silico study

G Kumar, R Patnaik - Medical hypotheses, 2016 - Elsevier
N-methyl-d-aspartate receptors (NMDARs) mediated excitotoxicity has been implicated in
multi-neurodegenerative diseases. Due to lack of efficacy and adverse effects of NMDA
receptor antagonists, search for herbal remedies that may act as therapeutic agents is an
active area of research to combat these diseases. Withania somnifera (WS) is being used for
centuries as a nerve tonic and Nootropic agents. The present study targets the in silico
evaluation of the neuroprotective efficacy of W. somnifera phytochemicals by inhibition of …

Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: an in silico study.

GK Gaurav Kumar, RP Ranjana Patnaik - 2016 - cabidigitallibrary.org
N-methyl-D-aspartate receptors (NMDARs) mediated excitotoxicity has been implicated in
multi-neurodegenerative diseases. Due to lack of efficacy and adverse effects of NMDA
receptor antagonists, search for herbal remedies that may act as therapeutic agents is an
active area of research to combat these diseases. Withania somnifera (WS) is being used for
centuries as a nerve tonic and Nootropic agents. The present study targets the in silico
evaluation of the neuroprotective efficacy of W. somnifera phytochemicals by inhibition of …
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