Expression of CK19 gene in patients with lung cancer and Its comparison with carcinoembryonic antigen in peripheral blood
A Mohamadnia, S Karimi, R Yadegar Azari… - Payavard …, 2016 - payavard.tums.ac.ir
Materials and Methods: Thirty patients with lung cancer (NSCLC type) were compared with
30 healthy controls. After taking peripheral blood samples and extracting total RNA, cDNA
was synthesized and examined by Real-time RT-PCR technique. Then, the CEA antigen
was measured by ELISA. Results: The CK19mRNA was positive in 7 out of 30 lung cancer
patients. Hence, its sensitivity was determined to be 23.3%. The serum level of CEA antigen
was positive in 11 out of 30 lung cancer patients. The mean serum level of CEA antigen …
30 healthy controls. After taking peripheral blood samples and extracting total RNA, cDNA
was synthesized and examined by Real-time RT-PCR technique. Then, the CEA antigen
was measured by ELISA. Results: The CK19mRNA was positive in 7 out of 30 lung cancer
patients. Hence, its sensitivity was determined to be 23.3%. The serum level of CEA antigen
was positive in 11 out of 30 lung cancer patients. The mean serum level of CEA antigen …
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