FSC-Q: a CryoEM map-to-atomic model quality validation based on the local Fourier shell correlation
In recent years, advances in cryoEM have dramatically increased the resolution of
reconstructions and, with it, the number of solved atomic models. It is widely accepted that
the quality of cryoEM maps varies locally; therefore, the evaluation of the maps-derived
structural models must be done locally as well. In this article, a method for the local analysis
of the map-to-model fit is presented. The algorithm uses a comparison of two local resolution
maps. The first is the local FSC (Fourier shell correlation) between the full map and the …
reconstructions and, with it, the number of solved atomic models. It is widely accepted that
the quality of cryoEM maps varies locally; therefore, the evaluation of the maps-derived
structural models must be done locally as well. In this article, a method for the local analysis
of the map-to-model fit is presented. The algorithm uses a comparison of two local resolution
maps. The first is the local FSC (Fourier shell correlation) between the full map and the …
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