Facile synthesis of benzofurans via copper-catalyzed aerobic oxidative cyclization of phenols and alkynes

W Zeng, W Wu, H Jiang, L Huang, Y Sun… - Chemical …, 2013 - pubs.rsc.org
W Zeng, W Wu, H Jiang, L Huang, Y Sun, Z Chen, X Li
Chemical Communications, 2013pubs.rsc.org
Regioselective synthesis of polysubstituted benzofurans using a copper catalyst and
molecular oxygen from phenols and alkynes in a one-pot procedure has been reported. The
transformation consists of a sequential nucleophilic addition of phenols to alkynes and
oxidative cyclization. A wide variety of phenols and alkynes can be used in the same
manner.
Regioselective synthesis of polysubstituted benzofurans using a copper catalyst and molecular oxygen from phenols and alkynes in a one-pot procedure has been reported. The transformation consists of a sequential nucleophilic addition of phenols to alkynes and oxidative cyclization. A wide variety of phenols and alkynes can be used in the same manner.
The Royal Society of Chemistry
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