[HTML][HTML] Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal reward contingency signals during rule-reversal
DH Trejo, A Ciuparu, PG da Silva, CM Velasquez… - bioRxiv, 2023 - ncbi.nlm.nih.gov
While animals readily adjust their behavior to adapt to relevant changes in the environment,
the neural pathways enabling these changes remain largely unknown. Here, using
multiphoton imaging, we investigated whether feedback from the piriform cortex to the
olfactory bulb supports such behavioral flexibility. To this end, we engaged head-fixed mice
in a multimodal rule-reversal task guided by olfactory and auditory cues. Both odor and,
surprisingly, the sound cues triggered cortical bulbar feedback responses which preceded …
the neural pathways enabling these changes remain largely unknown. Here, using
multiphoton imaging, we investigated whether feedback from the piriform cortex to the
olfactory bulb supports such behavioral flexibility. To this end, we engaged head-fixed mice
in a multimodal rule-reversal task guided by olfactory and auditory cues. Both odor and,
surprisingly, the sound cues triggered cortical bulbar feedback responses which preceded …
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