[HTML][HTML] Faster sensitivity loss around dense scotomas than for overall macular sensitivity in Stargardt disease: ProgStar Report No. 14
EM Schönbach, RW Strauss, MA Ibrahim… - American journal of …, 2020 - Elsevier
Purpose Mean sensitivity (MS) derived from a standard test grid using microperimetry is a
sensitive outcome measure in clinical trials investigating new treatments for degenerative
retinal diseases. This study hypothesizes that the functional decline is faster at the edge of
the dense scotoma (eMS) than by using the overall MS. Design Multicenter, international,
prospective cohort study: ProgStar Study. Methods Stargardt disease type 1 patients
(carrying at least 1 mutation in the ABCA4 gene) were followed over 12 months using …
sensitive outcome measure in clinical trials investigating new treatments for degenerative
retinal diseases. This study hypothesizes that the functional decline is faster at the edge of
the dense scotoma (eMS) than by using the overall MS. Design Multicenter, international,
prospective cohort study: ProgStar Study. Methods Stargardt disease type 1 patients
(carrying at least 1 mutation in the ABCA4 gene) were followed over 12 months using …
[PDF][PDF] Faster Sensitivity Loss around Dense Scotomas than for Overall Macular Sensitivity in Stargardt Disease: ProgStar Report No. 14
EMS NBACH, RW STRAUSS, MA IBRAHIM, JL JANES… - academia.edu
PURPOSE: Mean sensitivity (MS) derived from a standard test grid using microperimetry is a
sensitive outcome measure in clinical trials investigating new treatments for degenerative
retinal diseases. This study hypothesizes that the functional decline is faster at the edge of
the dense scotoma (eMS) than by using the overall MS. DESIGN: Multicenter, international,
prospective cohort study: ProgStar Study. METHODS: Stargardt disease type 1 patients
(carrying at least 1 mutation in the ABCA4 gene) were followed over 12 months using …
sensitive outcome measure in clinical trials investigating new treatments for degenerative
retinal diseases. This study hypothesizes that the functional decline is faster at the edge of
the dense scotoma (eMS) than by using the overall MS. DESIGN: Multicenter, international,
prospective cohort study: ProgStar Study. METHODS: Stargardt disease type 1 patients
(carrying at least 1 mutation in the ABCA4 gene) were followed over 12 months using …
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