Fecal microbiota transplantation reduces symptoms in some patients with irritable bowel syndrome with predominant abdominal bloating: short-and long-term results …
T Holvoet, M Joossens, JF Vázquez-Castellanos… - Gastroenterology, 2021 - Elsevier
Background & Aims Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder
associated with intestinal dysbiosis. Given the reported promising results of open-label fecal
microbiota transplantation (FMT) therapy in patients with predominant abdominal bloating,
we studied efficacy of this treatment in a randomized, placebo-controlled trial. Methods
Patients with refractory IBS, defined as failure of≥ 3 conventional therapies, were randomly
assigned to single-dose nasojejunal administration of donor stools (n= 43) or autologous …
associated with intestinal dysbiosis. Given the reported promising results of open-label fecal
microbiota transplantation (FMT) therapy in patients with predominant abdominal bloating,
we studied efficacy of this treatment in a randomized, placebo-controlled trial. Methods
Patients with refractory IBS, defined as failure of≥ 3 conventional therapies, were randomly
assigned to single-dose nasojejunal administration of donor stools (n= 43) or autologous …
[PDF][PDF] Fecal Microbiota Transplantation Reduces Symptoms in Some Patients With Irritable Bowel Syndrome With Predominant Abdominal Bloating: Short-and Long …
T Holvoet, M Joossens… - …, 2021 - lirias.kuleuven.be
BACKGROUND & AIMS: Irritable bowel syndrome (IBS) is a functional gastrointestinal
disorder associated with intestinal dysbiosis. Given the reported promising results of open-
label fecal microbiota transplantation (FMT) therapy in patients with predominant abdominal
bloating, we studied efficacy of this treatment in a randomized, placebo-controlled trial.
METHODS: Patients with refractory IBS, defined as failure of≥ 3 conventional therapies,
were randomly assigned to single-dose nasojejunal administration of donor stools (n= 43) or …
disorder associated with intestinal dysbiosis. Given the reported promising results of open-
label fecal microbiota transplantation (FMT) therapy in patients with predominant abdominal
bloating, we studied efficacy of this treatment in a randomized, placebo-controlled trial.
METHODS: Patients with refractory IBS, defined as failure of≥ 3 conventional therapies,
were randomly assigned to single-dose nasojejunal administration of donor stools (n= 43) or …
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