… The first total synthesis of the ichthyotoxic allomones (−)-… In conclusion, the first synthesis
of (−)-aplyolide A was achieved in ten steps with a non-optimized overall yield of 18%. …

… aplyolide A 91 (equation b, Scheme 12) where other methods failed. It is worthy of note that,
in the total synthesis of aplyolide A, … found to be essential and led to aplyolide in a 78% yield. …

… A convergent pathway is described for the synthesis of natural aplyolides A–E (1–5),
ichthyotoxic macrolides isolated from the skin of the marine mollusk Aplysia depilans. …

… The values of [α] D measured for synthetic aplyolides C and E were in accordance to those
… have accomplished the first total synthesis of potent ichthyotoxic macrolides aplyolides C 4 …

… marine source 4 and their preparation will provide enough material … aplyolide A (1);5., 6.
in this communication we present the first stereocontrolled total synthesis of natural aplyolides …

… and aplyolide A (103) (equation b, Scheme 12) where other methods failed. It is worthy of note
that, in the total synthesis of aplyolide A… to be essential and led to aplyolide in a 78% yield. …

… The total synthesis of the marine natural product (S)-(+)-chelonin B 15 was achieved and
reported in 2001. In this total synthesis, the vital reactions are the Sharpless asymmetric …

… the basis of an approach by Strenstrom for the first total synthesis of aplyolide A 25, 32 that
in turn allowed the absolute configuration of the single stereogenic centre to be determined. …

… The first total synthesis of the natural aplyolides B, C (43), D and E was achieved by Spinella
and Caruso by applying the Sharpless asymmetric dihydroxylation reaction to access the …

… [24] reported the synthesis of (À)-aplyolide A from 12 in which they adopted the Corey-… The
utility of Sonogashira macrocyclisation in the first total synthesis of penarolide sulfate A1, an α-…