Importance Neural tube defects are among the most common major congenital anomalies in
the United States and may lead to a range of disabilities or death. Daily folic acid
supplementation in the periconceptional period can prevent neural tube defects. However,
most women do not receive the recommended daily intake of folate from diet alone.
Objective To update the 2009 US Preventive Services Task Force (USPSTF)
recommendation on folic acid supplementation in women of childbearing age. Evidence …

Description: In 1996, the US Preventive Services Task Force (USPSTF) recommended that
all women planning or capable of pregnancy take a multivitamin supplement containing folic
acid for the prevention of neural tube defects. This recommendation is an update of the 1996
USPSTF recommendation. Methods: The USPSTF reviewed the evidence on folic acid
supplementation in women of childbearing age published since the 1996 USPSTF
recommendation. The USPSTF did not review the evidence on folic acid food fortification …