The present investigation deals with the formulation and evaluation of sodium alginate and
pectin based In situ gel of Losartan Potassium. Sodium alginate and guar gum were used as
a polymer and CaCO3 was used as a crosslinking agent. The formulation of gel depends
upon factors like temperature modulation, pH changes, presence of ions and ultra-violet
irradiation, from which drug gets released in sustained and controlled manner. The objective
of this study was to develop a novel in-situ gel. The system utilizes polymers that exhibit sol …