Introduction and aim Various taste masking approaches comprising the excipients which
delay the reach of the drug to taste buds are reported. Lipidic substances can act as release
retarding agent and provides a matrix base responsible for suppressing the bitter taste of
drug. This work was aimed to study the influence of different proportions of a lipid carrier on
the inhibition of bitterness of the drug vis-a-vis in vitro release of drug from the granules.
Methods The lipid-matrix granules of ondansetron HCl with Geleol pellets (glycerol …

Various taste masking approaches comprising the excipients which delay the reach of the
drug to taste buds are reported. Lipidic substances can act as release retarding agent and
provides a matrix base responsible for suppressing the bitter taste of drug. This work was
aimed to study the influence of different proportions of a lipid carrier on the inhibition of
bitterness of the drug vis-a-vis in vitro release of drug from the granules.