During the last few decades our understanding of the possible role of thyroid hormones
during brain development has increased and contributed to resolve previously discordant …

… 8 Morreale de Escobar G, Obregón MJ, Escobar del Rey F. Is neuropsychological development
related to maternal hypothyroidism, or to maternal hypothyroxinemia? Journal of Clinical …

In fungi and many other organisms, a thick outer cell wall is responsible for determining the
shape of the cell and for maintaining its integrity. The budding yeast Saccharomyces …

sigma is a DNA element of about 340 base pairs (bp) that is repeated many times in the yeast
genome. The element has 8-bp inverted repeats at its ends and is flanked by 5-bp direct …

Epidemiological studies from both iodine-sufficient and -deficient human populations strongly
suggest that early maternal hypothyroxinemia (ie, low circulating free thyroxine before …

… Francisco Escobar del Rey … The plasma was spun off and kept at −20 C, for the determination
of T 4 , T 3 , … at room temperature for 4 h, and stored at 4 C in PB containing 0.1 m sucrose. …

ENG1 (YNR067c), a gene encoding a new endo-1,3-β-glucanase, was cloned by screening
a genomic library with a DNA probe obtained by PCR with synthetic oligonucleotides …

… For Experiment C we processed 7 different tissues from each of the five dams, and the PI
and L from their 64 fetuses. To increase accuracy of the determination of [1 2 5|]T4 in 'eta' …

ABSTRACT: We have studied the ontogenesis of 5′-deiodinase (5′ D) activity in rat brain
during fetal life, its capacity to respond to maternal or fetal hypothyroidism, and its regulation …

… ) to early log phase (OD 595 =0.5) and then shifting the cultures to 37C for 4 hours. Cells
were released from arrest by transfer to 25C, and samples were taken every 20 minutes. …