[HTML][HTML] Functional activity of maternal and cord antibodies elicited by an investigational group B Streptococcus trivalent glycoconjugate vaccine in pregnant women
Objectives The main aim of this exploratory study was to evaluate functional activity of
antibodies elicited by a maternal Group B Streptococcus (GBS) investigational vaccine
composed of capsular polysaccharides Ia, Ib, and III conjugated to genetically detoxified
Diphtheria toxin CRM 197. The second objective was to investigate the relationship between
serotype-specific IgG concentrations and functional activity in maternal and cord sera.
Methods Maternal and cord sera collected at baseline and at delivery from vaccine and …
antibodies elicited by a maternal Group B Streptococcus (GBS) investigational vaccine
composed of capsular polysaccharides Ia, Ib, and III conjugated to genetically detoxified
Diphtheria toxin CRM 197. The second objective was to investigate the relationship between
serotype-specific IgG concentrations and functional activity in maternal and cord sera.
Methods Maternal and cord sera collected at baseline and at delivery from vaccine and …
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