GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates
N Roca-Ayats, S Balcells, N Garcia-Giralt… - … England Journal of …, 2017 - Mass Medical Soc
N Roca-Ayats, S Balcells, N Garcia-Giralt, M Falco-Mascaro, N Martinez-Gil, JF Abril…
New England Journal of Medicine, 2017•Mass Medical SocThis letter describes the detection of GGPS1 and other mutations in three sisters who had
atypical femoral fractures associated with long-term bisphosphonate use, which suggests
that genes in the isoprenoid biosynthetic pathway may confer susceptibility to atypical
fractures.
atypical femoral fractures associated with long-term bisphosphonate use, which suggests
that genes in the isoprenoid biosynthetic pathway may confer susceptibility to atypical
fractures.
This letter describes the detection of GGPS1 and other mutations in three sisters who had atypical femoral fractures associated with long-term bisphosphonate use, which suggests that genes in the isoprenoid biosynthetic pathway may confer susceptibility to atypical fractures.
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