… mitochondria function and to scavenge oxidative stress [35, 38, … test whether GM1 and its
oligosaccharide were able to inhibit … portion of GM1 was sufficient in preventing the glutamate …

… pro-inflammatory activity. The anti-inflammatory effects of GM1 and other gangliosides were
… increasing endogenous ganglioside levels with L–t-PDMP, whereas inhibition of glycolipid …

… of OligoGM1 reduced the cellular oxidative stress in Neuro2a cells and … molecules and
inhibition of oxidative stress. Sirtuins, for … The neuroprotective properties of GM1 ganglioside have …

… Oxidative stress is an … that gangliosides prevent kainate neurotoxicity in primary neuronal
cultures of neonatal rat cerebellum and cortex. It has been reported that gangliosides inhibit the …

… Multiple studies have revealed that propofol causes hippocampal injury and cognitive … by
inhibiting inflammatory responses, excitotoxicity responses, and oxidative stress responses and …

… by p38 MAPK, preventing oxidative stress and reducing N2a cell … Interestingly, the selective
inhibition of TrkA kinase activity, … Pretreatment of N2a with a specific IP3 receptor inhibitor …

… inhibiting mitochondrial complex I which, in turn, leads to energy deprivation, oxidative stress
increase and finally to cell damage … from MPTP-induced oxidative stress and cell death …

… Natural gangliosides were recently proposed to prevent cells … In summary, this study
demonstrates that GM1 exhibits … to the inhibition of the apoptosis induced by ER stress in vivo. …

… decrease DNA fragmentation and act as H 2 O 2 inhibitors … For example, treatment with GM1
protects against oxidative stress… signal from the EGFR prevents one of the three downstream …

… potential of gangliosides; and (iii) inhibition of hydrogen … If oxidative stress and apoptosis
are chemically induced in … , exposure to the monosialoganglioside GM1 inhibits ROS and lipid …