[HTML][HTML] Galacto-oligosaccharides protect the intestinal barrier by maintaining the tight junction network and modulating the inflammatory responses after a challenge …

P Akbari, S Braber, A Alizadeh, KAT Verheijden… - The Journal of …, 2015 - Elsevier
Background: The integrity of the epithelial layer in the gastrointestinal tract protects
organisms from exposure to luminal antigens, which are considered the primary cause of
chronic intestinal inflammation and allergic responses. The common wheat-associated
fungal toxin deoxynivalenol acts as a specific disruptor of the intestinal tight junction network
and hence might contribute to the pathogenesis of inflammatory bowel diseases. Objective:
The aim of the current study was to assess whether defined galacto-oligosaccharides …
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