Gastric mucosal interleukine-8 (IL-8) and interleukine-1beta (IL-1ß) levels in atrophic gastritis and gastric carcinoma patients.
AHM Al-Faisal - Journal of the Faculty of Medicine …, 2008 - iqjmc.uobaghdad.edu.iq
Journal of the Faculty of Medicine Baghdad, 2008•iqjmc.uobaghdad.edu.iq
Background: Cytokines are the messengers of the immune system. They are mostly secreted
by macrophages and lymphocytes and their production is induced in response to injury or
infections. Objective: Biopsy speciemens from the middle body of the stomach were
obtained from 18 patients with gastric carcinoma, 32 patients with atrophic gastritis, 50
patients with chronic gastritis and 20 healthy subjects and IL-8 and IL-1B levels were
detrmined. Methods: Sandwich-type enzyme-linked immunosorbent assay kit was used to …
by macrophages and lymphocytes and their production is induced in response to injury or
infections. Objective: Biopsy speciemens from the middle body of the stomach were
obtained from 18 patients with gastric carcinoma, 32 patients with atrophic gastritis, 50
patients with chronic gastritis and 20 healthy subjects and IL-8 and IL-1B levels were
detrmined. Methods: Sandwich-type enzyme-linked immunosorbent assay kit was used to …
Background
Cytokines are the messengers of the immune system.They are mostly secreted by macrophages and lymphocytes and their production is induced in response to injury or infections.
Objective
Biopsy speciemens from the middle body of the stomach were obtained from 18 patients with gastric carcinoma, 32 patients with atrophic gastritis, 50 patients with chronic gastritis and 20 healthy subjects and IL-8 and IL-1B levels were detrmined.
Methods
Sandwich-type enzyme-linked immunosorbent assay kit was used to determine the IL-8 and IL-1B levels.
Results
IL-8 and IL-1B levels were significantly higher in gastric carcinoma patients than patients with atrophic gastritis and both significantly higher than healthy subjects.
Conclusions
IL-8 and IL-1B levels were recommended to be used in differentiation between gastric carcinoma and atrophic gastritis.
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