Gastrointestinal nematode challenge induces some conserved gene expression changes in the gut mucosa of genetically resistant sheep

A Ingham, A Reverter, R Windon, P Hunt… - International journal for …, 2008 - Elsevier
Sheep have a varying ability to resist infection with gastrointestinal nematodes. This ability is
due in part to genetic differences that exist between individuals. In order to define these
differences we have used real-time PCR to quantify gene expression responses in the gut
mucosal surface of genetically resistant and susceptible sheep, following a nematode
challenge. Expression profiles were determined in response to two different nematode
species, Haemonchus contortus and Trichostrongylus colubriformis, and in divergent sheep …
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