[HTML][HTML] Gene expression profiling of multi-drug resistant E. coli after exposure by nanomolecular iodine-containing complex

I Korotetskiy, S Shilov, O Reva, TV Kuznetsova… - News Natl. Acad. Sci …, 2020 - azdok.org
I Korotetskiy, S Shilov, O Reva, TV Kuznetsova, AB Jumagaziyeva, NB Akhmatullina, AI Ilin
News Natl. Acad. Sci. Repub. Kazakhstan, 2020azdok.org
… This study aimed to carry out the total gene expression profiling to assess the effects of the
drug FS-1 inducing antibiotic resistance reversion in the model multidrug-resistant strain E. coli
ATCC® BAA-199 during its cultivation with FS-1. … To visualize the results and compare gene
expression profiles, we applied our in-house scripts written on Python 2.5. The differential …
Abstract
Gene profiling was performed to assess the transcriptomic effect of the FS-1 drug during long-term exposure to the multidrug-resistant strain of E. coli ATCC® BAA-199. FS-1 was added to the E. coli culture at a concentration corresponding to 1/2 MBC for ten passages.
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