Background Myocarditis is characterized by the presence of an inflammatory infiltrate in the
myocardium with degenerative/necrotic changes of cardiomyocytes, not-related to ischemic
damage. Its clinical presentation is extremely heterogenous1. Endomyocardial Biopsy
(EMB) is the diagnostic gold standard and provides etiopathogenetic diagnosis. Biopsy-
proven myocarditis may be infectious, mainly viral, toxic o non-infectious immune-
mediated/autoimmune. A complex interplay between genetic factors, environmental triggers …

Genetic characterization of biopsy-proven myocarditis: a pilot study Background Myocarditis
is characterized by the presence of an inflammatory infiltrate in the myocardium with
degenerative/necrotic changes of cardiomyocytes, not-related to ischemic damage. Its
clinical presentation is extremely heterogenous. Endomyocardial Biopsy (EMB) is the
diagnostic gold standard and provides etiopathogenetic diagnosis. Biopsy-proven
myocarditis may be infectious, mainly viral, toxic or non-infectious immune …