10 天前 - … differences, but the underlying mechanisms remain poorly … of postmortem brain
samples from patients with schizophrenia (… transcriptomic burden genes and genes identified by …

51 天前 - … , shedding light on the underlying mechanisms of cognitive deficits observed in …
brain area has been linked to cue detection and attentional performance [8-10]. Schizophrenia (…

60 天前 - … two genes known to escape XCI, (XIST and JPX), underlying the … genes associated
with sex-speci c OCRs, we performed gene set enrichment analysis (GSEA) in each cell type…

134 天前 - … brain disorders—schizophrenia, depression, and Alzheimer’s disease—and facilitates
mapping causal genes to particular cell types. … underlying the three aforementioned brain …

223 天前 - … disorder, epilepsy, and schizophrenia. Patients have diverse … which had underlying
changes to cell adhesion pathways. … with pAdj <0.05 and genes identified in the Uddin and …

246 天前 - … to better characterize underlying mechanisms of normal … cell-type specific differentially
expressed (DE) genes and … psychiatric disorder, mainly schizophrenia. With roughly 800 …

246 天前 - … We identified dramatic cell-type-specific shifts in DNA … sites amongst genomic
regions implicated in schizophrenia. … -type underlying epigenetic dysregulation in disease. …

246 天前 - … schizophrenia, mood disorders, substance use, and eating disorders. … identify
potential cellular mechanisms underlying BMI-induced dysfunction in the brain mediated by cell …

290 天前 - … Psychiatric manifestations, such as psychosis and mood … distinct types of abnormally
misfolded proteins: TAR DNA-… which reliably point to underlying pathology will improve …

311 天前 - … mutations show that many genetic differences in schizophrenia converge on synaptic
… in postmortem brains may reflect the intrinsic complex genetic risk in schizophrenia which …