Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

CR Bhasker, W McKinnon, A Stone… - Pharmacogenetics …, 2000 - journals.lww.com
UGT2B7 catalyses the glucuronidation of a diverse range of drugs, environmental chemicals
and endogenous compounds. Hence, coding region polymorphisms of UGT2B7 are
potentially of pharmacological, toxicological and physiological significance. Two variant
UGT2B7 cDNAs encoding enzymes with either His or Tyr at residue 268 have been isolated.
The variants, referred to as UGT2B7* 1 and UGT2B7* 2, respectively, arise from a C to T
transversion at nucleotide 802 of the UGT2B7 coding region. Analysis of genomic DNA from …
被引用次数：300 相关文章 所有 9 个版本

[引用][C] Genetic polymorphism of UDP-glucronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

CR Bhasker - Pharmacogenetics, 2000 - cir.nii.ac.jp
Genetic polymorphism of UDP-glucronosyltransferase 2B7 (UGT2B7) at amino acid 268 :
ethnic diversity of alleles and potential clinical significance | CiNii Research … Genetic
polymorphism of UDP-glucronosyltransferase 2B7 (UGT2B7) at amino acid 268 : ethnic
diversity of alleles and potential clinical significance …
被引用次数：1 相关文章
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