[HTML][HTML] Genetic variation in fibrinogen; its relationship to fibrinogen levels and the risk of myocardial infarction and ischemic stroke

B Siegerink, FR Rosendaal, A Algra - Journal of thrombosis and …, 2009 - Elsevier
… This study assessed the risk implications of genetic variations in the fibrinogen module on
… of the genetic variants FGA Thr312Ala and FGB − 455G/A as markers for altered fibrinogen

Role of genetic variation at the fibrinogen locus in determination of plasma fibrinogen concentrations

SE Humphries, M Dubowitz, M Cook, Y Stirling… - The Lancet, 1987 - Elsevier
… look for genetic variation at this locus in relation to plasma fibrinogenfibrinogen values
being in the groups with the genotype T1T1 and AIA2 (table l). We estimate that genetic variation

Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen γ′ levels

S Uitte de Willige, MCH de Visser… - Blood, 2005 - ashpublications.org
… We hypothesized that relatively common variations among the fibrinogen genes might exist
… Such variations would be part of the existing haplotypes and might affect fibrinogen levels, …

Genetic variation at the beta-fibrinogen locus in relation to plasma fibrinogen concentrations and risk of myocardial infarction. The ECTIM Study.

PY Scarabin, L Bara, S Ricard, O Poirier… - … and Thrombosis: A …, 1993 - Am Heart Assoc
… "16 In addition, whether fibrinogen genotype is associated with the IHD risk has not … 0-fibrinogen
gene17 to investigate the genetic variation at this locus in relation to plasma fibrinogen

[HTML][HTML] Fibrinogen gene variation and ischemic stroke

K Jood, J Danielson, C Ladenvall, C Blomstrand… - Journal of Thrombosis …, 2008 - Elsevier
variation in another Swedish population [25]. In this study, selected parts of the FGG, FGA,
and FGB genes were … data to capture the genetic variation over the fibrinogen gene cluster. In …

Genetic variation at fibrinogen loci and plasma fibrinogen levels.

JM Connor, FG Fowkes, J Wood, FB Smith… - … of medical genetics, 1992 - ncbi.nlm.nih.gov
… etic variation at the fibrinogen loci and plasma fibrinogen levels… ) fibrinogen loci in 247
subjects whose plasma fibrinogen was … Plasma fibrinogen levels, by either assay method, when …

Fibrinogen and cardiovascular disease: genetics and biomarkers

D Tousoulis, N Papageorgiou, E Androulakis… - Blood reviews, 2011 - Elsevier
… common genetic variation across the fibrinogen genes was … The effect of genetic variation
on plasma fibrinogen levels, … interaction between genetic variation in the fibrinogen b promoter …

Fibrinogen gene regulation

RJ Fish, M Neerman-Arbez - Thrombosis and haemostasis, 2012 - thieme-connect.com
… This variation between individuals is influenced by genotype, suggesting there are genetic
variants contributing to fibrinogen levels which reside in fibrinogen regulatory loci. A complete …

Genetic variation in the promoter region of the β-fibrinogen gene is associated with ischemic stroke in a Japanese population

S Nishiuma, K Kario, K Yakushijin… - Blood coagulation & …, 1998 - journals.lww.com
… different genes (a, f, y) on the long arm of chromosome 4 [4]. Recently, genetic variations at
the fibrinogen loci … In particular, the 6 fibrinogen gene appears to play an important role in the …

[HTML][HTML] Elevated plasma fibrinogen γ′ concentration is associated with myocardial infarction: effects of variation in fibrinogen genes and environmental factors

MN Mannila, RS Lovely, SC Kazmierczak… - Journal of Thrombosis …, 2007 - Elsevier
genetic variation in the FGG gene and in the splicing machinery is likely to contribute, partly
account for the variation … the plasma fibrinogen γ′ and total fibrinogen concentration noted …