Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria
Beneficial microorganisms are widely used in agriculture for control of plant pathogens, but
a lack of efficacy and safety information has limited the exploitation of multiple promising
biopesticides. We applied phylogeny-led genome mining, metabolite analyses and
biological control assays to define the efficacy of Burkholderia ambifaria, a naturally
beneficial bacterium with proven biocontrol properties but potential pathogenic risk. A panel
of 64 B. ambifaria strains demonstrated significant antimicrobial activity against priority plant …
a lack of efficacy and safety information has limited the exploitation of multiple promising
biopesticides. We applied phylogeny-led genome mining, metabolite analyses and
biological control assays to define the efficacy of Burkholderia ambifaria, a naturally
beneficial bacterium with proven biocontrol properties but potential pathogenic risk. A panel
of 64 B. ambifaria strains demonstrated significant antimicrobial activity against priority plant …
[引用][C] Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria. Nat Microbiol 4: 996–1005
AJ Mullins, JAH Murray, MJ Bull, M Jenner, C Jones… - 2019
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