Genomic survey of SARS-CoV-2 vaccine breakthrough infections in healthcare workers from Kerala, India

B Jolly, N John, RC Bhoyar, N Majeed… - Journal of …, 2021 - journalofinfection.com
… We surmise that genomic surveillance is useful to understand and monitor evolving SARS-CoV-2
variants. In this study, we describe the genomic characterization of vaccine breakthrough
infections following vaccination in 6 healthcare workers (P1–P6) from Kerala, India. All 6
patients were fully vaccinated with two standard doses of the AZD1222/Covishield vaccine. …

[PDF][PDF] Genomic survey of SARS-CoV-2 vaccine breakthrough infections in healthcare workers from Kerala, India

A Joseph, MK Divakar, PR Nair, A Shamnath… - academia.edu
We describe genomic analysis of SARS-CoV-2 isolates from breakthrough infections in six
healthcare workers following vaccination with AZD1222/Covishield. Four patients were
infected by the variant of concern B. 1.1. 7 while other isolates possessed E484K and
S477N mutations in spike protein associated with immune escape.
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