过去一年中添加的文章,按日期排序

Combining omics approaches to evaluate biomarkers for complex brain disorders

MR Francia - 2024 - escholarship.org
2 天前 - … various aspects of Alzheimer's Disease pathology as … the utility of integrating
functional genomics platforms to … and disorders. Additionally, through CSF metabolomics ii …

Study: 2 APOE4 Copies May Indicate Genetic Form of Alzheimer Disease

E Harris - JAMA - jamanetwork.com
2 天前 - … The findings suggest that being homozygous forAPOE4is more than just a risk
factor for Alzheimer disease—it genetically determines whether people develop it, the …

Decoding Shared Genetics: Unveiling the Link Between Major Depressive Disorder and Glioblastoma Multiforme

H Tian - BIO Web of Conferences, 2024 - bio-conferences.org
3 天前 - … the hippocampus of patients with Alzheimer's disease, which is closely related to
patients' … At the same time, related genomic studies have proven that the UBE2C gene locus is …

Post‐GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3

DJ Panyard, LM Reus, M Ali, J Liu… - Alzheimer's & …, 2024 - Wiley Online Library
4 天前 - … novel CSF proteomics discovery and replication analyses, and the supporting
transcriptomic and functional genomic data sets and resources that were used in this study. AD, …

[HTML][HTML] The Role of TOMM40 in Cardiovascular Mortality and Conduction Disorders: An Observational Study

G Di Stolfo, S Mastroianno, N Soldato… - Journal of Clinical …, 2024 - mdpi.com
5 天前 - … 31A > G and it has been linked to Alzheimer disease, apolipoprotein and … genomic
contribution of TOMM40 SNPs to cardiovascular deaths and cardiac conduction diseases

Epigenetics and environmental health

M Zhang, T Hu, T Ma, W Huang, Y Wang - Frontiers of Medicine, 2024 - Springer
5 天前 - … can regulate the state of development and lead to developmental disorders,
aging, cardiovascular disease, Alzheimer’s disease, cancers, and so on. However, epigenetic …

[HTML][HTML] Causal relationships between gut microbiota and dementia: A two-sample, bidirectional, Mendelian randomization study

ZL Ren, HH Zhou, CP Chen, H He, DL Wang… - World Journal of Clinical …, 2024 - wjgnet.com
5 天前 - … publicly available gut microbiota-related genome-wide association study (GWAS)
sum … Gut microbiota regulate Alzheimer's disease pathologies and cognitive disorders via …

[HTML][HTML] Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer's disease

J Xie, Y Lan, C Zou, J He, Q Huang, J Zeng, M Pan… - … genomics, 2024 - ncbi.nlm.nih.gov
5 天前 - … expression genes using the Wilcoxon rank-sum test with the FindAllMarkers function
… Additionally, annotation and reclustering were performed based on functional genes [22…

The Neurodegenerative Disease Knowledge Portal: Propelling Discovery Through the Sharing of Neurodegenerative Disease Genomic Resources

AA Dilliott, MC Costanzo, NP Burtt, S Bandres-Ciga… - medRxiv, 2024 - medrxiv.org
5 天前 - … New insights into the genetic etiology of Alzheimer's diseasegenomic variants in
wholegenome sequencing datasets reveal two novel Alzheimer's disease-associated genes: …

Inhibitor of bromodomain and extraterminal domain proteins decreases transcription of Cd33 in the brain of mice subjected to systemic inflammation; a promising …

GA Czapski, M Matuszewska, M Cieślik… - Folia …, 2024 - termedia.pl
6 天前 - … neurodegenerative disorders, including Alzheimer’s disease (… in transcription of
several genes, thus controlling these … Since genome-wide association studies showed that the …