Gentamicin Augments the Quorum Quenching Potential of Cinnamaldehyde In Vitro and Protects Caenorhabditis elegans From Pseudomonas aeruginosa Infection

J Chadha, Ravi, J Singh, S Chhibber… - Frontiers in Cellular and …, 2022 - frontiersin.org
… The quorum sensing (QS) circuitry of Pseudomonas aeruginosa represents an attractive …
quorum quenching (QQ) potential of cinnamaldehyde (CiNN) in combination with gentamicin (…

Repurposing carvacrol, cinnamaldehyde, and eugenol as potential anti-quorum sensing agents against uropathogenic Escherichia coli isolates in Alexandria, Egypt

HA Morgaan, HMG Omar, AS Zakaria, NM Mohamed - BMC microbiology, 2023 - Springer
… Subsequently, we present an in vitro assessment of the combined effect of these agents …
The hazard of biofilm formation by UPEC isolates tends to augment with prolonged …

trans-Cinnamaldehyde as a Novel Candidate to Overcome Bacterial Resistance: An Overview of In Vitro Studies

F Usai, A Di Sotto - Antibiotics, 2023 - mdpi.com
… exhibited a quorum quenching (QQ) potential, being able to … of cinnamaldehyde in combination
with gentamicin were also … in cinnamaldehyde as a possible anti-quorum sensing agent …

Enhancing commercial antibiotics with trans-cinnamaldehyde in Gram-positive and Gram-negative bacteria: An in vitro approach

N Ferrando, MR Pino-Otín, D Ballestero, G Lorca… - Plants, 2024 - mdpi.com
… and, moreover, they help protect the plant against harmful stress … of the potential synergistic
benefits of cinnamaldehyde … genes related to the Quorum Sensing-Fsr system [53], whose …

α-Terpineol synergizes with gentamicin to rescue Caenorhabditis elegans from Pseudomonas aeruginosa infection by attenuating quorum sensing-regulated …

J Chadha, J Singh, K Harjai - Life Sciences, 2023 - Elsevier
… aeruginosa, in conjunction with gentamicin (GeN) in vitro. We … recently reported with the
cinnamaldehyde-GeN combination … our hypothesis that GeN augments the anti-QS potential of α-…

Cinnamaldehyde induces expression of efflux pumps and multidrug resistance in Pseudomonas aeruginosa

A Tetard, A Zedet, C Girard, P Plésiat… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
… interesting properties in vitro against various pathogens, including … on bacterial resistance
to gentamicin, tobramycin, and … Furthermore, by antagonizing the quorum sensing regulatory …

Inhibitory effect of natural compounds on quorum sensing system in Pseudomonas aeruginosa: a helpful promise for managing biofilm community

A Shariati, M Noei, M Askarinia… - Frontiers in …, 2024 - frontiersin.org
… of cinnamaldehyde and gentamycin demonstrated a synergistic effect and showed potential
action … effectiveness using in vivo models in order to utilize its potential for combating virulent …

Repurposing phytochemicals as anti‐virulent agents to attenuate quorum sensing‐regulated virulence factors and biofilm formation in Pseudomonas aeruginosa

J Chadha, K Harjai, S Chhibber - Microbial biotechnology, 2022 - Wiley Online Library
… and augmentation of virulence factors in P. aeruginosa. … , eugenol, carvacrol and
cinnamaldehyde, the lactone ring is … studies in vitro and experiments with animal models in vivo. …

Design of cinnamaldehyde-and gentamicin-loaded double-layer corneal nanofiber patches with antibiofilm and antimicrobial effects

S Cesur, E Ilhan, TA Tut, E Kaya, B Dalbayrak… - ACS …, 2023 - ACS Publications
… In this study, PVA/GEL nanofibers enriched with cinnamaldehyde and gentamicin were …
features, and in vitro cell viability of the gentamicin-and cinnamaldehyde-loaded nanofiber …

Inhibitory effects of Cinnamaldehyde, Carvacrol, and honey on the expression of exoS and ampC genes in multidrug-resistant Pseudomonas aeruginosa isolated from …

Z Mohammadzamani, A Khorshidi, A Khaledi… - Microbial …, 2020 - Elsevier
… , augments the invasion to nonphagocytic cells, induces programmed cell death in epithelial
cells, lymphocytes and fibroblasts, and protects … in burn patients by protecting the bacterium …