Geraniol modulates tongue and hepatic phase I and phase II conjugation activities and may contribute directly to the chemopreventive activity against experimental …
A Madankumar, S Jayakumar, K Gokuladhas… - European Journal of …, 2013 - Elsevier
Xenobiotic metabolizing enzymes are chief determinants in both the susceptibility to
mutagenic effect of chemical carcinogens and in the response of tumors to chemotherapy.
The present study was aimed to analyze the effect of geraniol administration on the activity
of phase I and phase II carcinogen metabolizing enzymes through the nuclear factor
erythroid 2-related factor-2 (Nrf2) activation against 4-niroquinoline-1-oxide (4NQO) induced
oral carcinogenesis. The well-known chemical carcinogen 4NQO (50ppm) was used to …
mutagenic effect of chemical carcinogens and in the response of tumors to chemotherapy.
The present study was aimed to analyze the effect of geraniol administration on the activity
of phase I and phase II carcinogen metabolizing enzymes through the nuclear factor
erythroid 2-related factor-2 (Nrf2) activation against 4-niroquinoline-1-oxide (4NQO) induced
oral carcinogenesis. The well-known chemical carcinogen 4NQO (50ppm) was used to …
Geraniol modulates tongue and hepatic phase I and phase II conjugation activities and may contribute directly to the chemopreventive activity against experimental …
AM Arumugam Madankumar… - 2013 - cabidigitallibrary.org
Xenobiotic metabolizing enzymes are chief determinants in both the susceptibility to
mutagenic effect of chemical carcinogens and in the response of tumors to chemotherapy.
The present study was aimed to analyze the effect of geraniol administration on the activity
of phase I and phase II carcinogen metabolizing enzymes through the nuclear factor
erythroid 2-related factor-2 (Nrf2) activation against 4-niroquinoline-1-oxide (4NQO) induced
oral carcinogenesis. The well-known chemical carcinogen 4NQO (50 ppm) was used to …
mutagenic effect of chemical carcinogens and in the response of tumors to chemotherapy.
The present study was aimed to analyze the effect of geraniol administration on the activity
of phase I and phase II carcinogen metabolizing enzymes through the nuclear factor
erythroid 2-related factor-2 (Nrf2) activation against 4-niroquinoline-1-oxide (4NQO) induced
oral carcinogenesis. The well-known chemical carcinogen 4NQO (50 ppm) was used to …
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