Glutamate-gated NMDA receptors: insights into the function and signaling in the kidney

JM Valdivielso, À Eritja, M Caus, M Bozic - Biomolecules, 2020 - mdpi.com
… N-Methyl-d-aspartate receptor (NMDAR) is a glutamate-gated ionotropic receptor that
intervenes in most of the excitatory synaptic transmission within the central nervous system (CNS). …

Glutamate ionotropic receptor NMDA type subunit 1: A novel potential protein target of dapagliflozin against renal interstitial fibrosis

Y Liu, Y Wang, S Chen, L Bai, F Li, Y Wu… - European journal of …, 2023 - Elsevier
… enriched in Chemokine signaling pathway, NOD-like receptor signaling pathway, PI3K-Akt …
To gain further insight into the conformational transition behind the GRIN1-dapagliflozin …

[PDF][PDF] Glutamate-Gated NMDA Receptors: Insights into the Function and Signaling in the Kidney

JM Valdivielso Revilla, À Eritja, M Caus Enríquez… - 2020 - repositori.udl.cat
… Abstract: N-Methyl-D-aspartate receptor (NMDAR) is a glutamate-gated ionotropic receptor
that intervenes in most of the excitatory synaptic transmission within the central nervous …

Monosodium glutamate altered renal architecture and modulated expression of NMDA-R, eNOS, and nNOS in normotensive and hypertensive rats

N Thongsepee, W Himakhun, K Kankul… - Food and Chemical …, 2024 - Elsevier
… altered the renal architecture but also modified the functional proteins … of renal physiological
functions. N-methyl-D-aspartate receptor (NMDA-R) is a glutamate-gated ionotropic receptor

NMDA receptor blocker ameliorates ischemia-reperfusion-induced renal dysfunction in rat kidneys

CC Yang, CT Chien, MH Wu… - … of Physiology-Renal …, 2008 - journals.physiology.org
… Previous results illustrate that glutamate-gated NMDA and non-NMDA receptors are
important routes in mediating NF-κB activation during brain ischemic injury. Active NF-κB may, in …

Renal NMDA receptors independently stimulate proximal reabsorption and glomerular filtration

A Deng, SC Thomson - … Journal of Physiology-Renal …, 2009 - journals.physiology.org
about the functional role of NMDA-Rs in the kidney is that they might mediate the selective
renal … Hence, if the body invokes renal NMDA-R signaling in its response to dietary protein (21)…

Ligand-gated ion channels: new insights into neurological disorders and ligand recognition

D Lemoine, R Jiang, A Taly, T Chataigneau… - Chemical …, 2012 - ACS Publications
insights into the mechanism that underlies cell signaling at the … α4β2(V287L) nAChRs in
human embryonic kidney (HEK)-293 cells … Considering the crucial role of NMDA receptors in …

The role of the TNFα-mediated astrocyte signaling pathway in epilepsy

R Chen, G Xue, C Hölscher - Acta Epileptologica, 2021 - Springer
… epilepsy and provides insights into the potential therapeutic … The AMPA receptor is a
glutamate-gated ion channel that … of kidney type glutaminase (KGA) via the STAT3 signaling

NMDA receptors, neural pathways, and protein interaction databases

H Husi - International review of neurobiology, 2004 - Elsevier
… new insights into cellular regulation and the machinery of signal … methods to detect functional
linkages among predicted … NMDA and AMPA⧸kainate receptors act as glutamate-gated

Mechanistic insights to the Ca2+-dependent inactivation of NMDA receptors by Calmodulin

GJ Iacobucci - 2018 - search.proquest.com
… of NMDA receptors and provide new insight into Ca2+-… (iGluR) family encompasses
structurally related glutamate-gated … biochemical signals to initiate both functional and structural …