…, T Esko, C Hayward, JF Wilson, G Lauc… - … Molecular Genetics, 2021 - academic.oup.com
… involved in regulation of glycosylation biochemical pathways. … N-glycosylation and to investigate possible pleiotropic effects … network and proposed new regulators of IgG glycosylation. …
… that have a big effect on glycosylation, many other genes with … Pleiotropy between glycosylation and gene expression was … the network analysis for non-glycosylationgenes influencing …
… To identify genetic loci associated with IgG glycosylation, we quantitated N-linked IgG glycans … 16 genetic loci that are likely to be part of a much largergeneticnetwork that regulates the …
X Li, H Wang, Y Zhu, W Cao, M Song, Y Wang… - Frontiers in …, 2021 - frontiersin.org
… regulatedgenes associated with IgG N-glycosylation traits … (PPI) network for the connectivity of the genes by GeneNetwork v2.… The pleiotropicgene findings in this study can confirm that …
… A complex dynamic network, including genetic and epigenetic factors, regulates the … far is immunoglobulinG (IgG) (17). Its glycosylation is thought to have important regulatory functions …
… of the geneticregulation of the populational variation of … and the N-glycosylation of immunoglobulinG and transferrin. While … genetic region may be due to pleiotropic effects of the …
… a general regulatory effect influencing the glycosylation of … large variability of plasma proteins and immunoglobulinG (… N-glycosylation of human immunoglobulinG show pleiotropy …
… b Correlation network of IgA and IgG N-linked glycosylation derived traits. Each node … -glycosylation, suggesting shared genetic and environmental mechanisms of immune regulation to …
… The identified loci were also shown to be pleiotropic with … the genes involved in the process of IgG N-glycosylation by … The complex regulatorynetwork behind protein glycosylation …