Granulocytic sarcoma of the small intestine with CBFβ/MYH11 fusion gene: report of an aleukaemic case and review of the literature
SG Xavier, EM Fagundes, R Hassan, C Bacchi… - Leukemia research, 2003 - Elsevier
Granulocytic sarcomas (GS) are rare extramedullary tumours composed of immature
myeloid cells. Inversion of chromosome 16 [inv (16)] is a cytogenetic marker for M4Eo
subtype of acute myeloid leukaemia (AML). The possibility of an association between the
development of granulocytic sarcoma of the small intestine (GSSI) and the M4Eo subtype of
AML was suggested in nine previous case reports. Here we report an aleukaemic case of
GSSI with inv (16) and its molecular equivalent, the CBFβ/MYH11 fusion gene, detected by …
myeloid cells. Inversion of chromosome 16 [inv (16)] is a cytogenetic marker for M4Eo
subtype of acute myeloid leukaemia (AML). The possibility of an association between the
development of granulocytic sarcoma of the small intestine (GSSI) and the M4Eo subtype of
AML was suggested in nine previous case reports. Here we report an aleukaemic case of
GSSI with inv (16) and its molecular equivalent, the CBFβ/MYH11 fusion gene, detected by …
以上显示的是最相近的搜索结果。 查看全部搜索结果