Objective The passive properties of the venous wall are important for the compliance
function of the venous system. The objective of this study was to quantify the passive
biomechanical response and structural growth and remodeling of veins subjected to chronic
venous reflux and hypertension. Methods To investigate the effects of venous reflux on
venous mechanics, the tricuspid valve was injured in a canine model by disrupting the
chordae tendineae. The conventional inflation-extension protocol in conjunction with …