1The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Bournemouth,
2Northern Genetics Service, Newcastle upon Tyne, 3St Bartholomew's Hospital, Barts
Health NHS Trust, 4Barts and The London School of Medicine and Dentistry, Queen Mary
University of London and Barts Health NHS Trust, London, 5Addenbrooks Hospital,
University of Cambridge, Cambridge, 6Leeds Teaching Hospitals, Leeds, 7Kings College
Hospital NHS Foundation Trust, London, 8Sheffield Teaching Hospitals NHS Foundation …

Pancytopenia with hypocellular bone marrow is the hallmark of aplastic anaemia (AA) and
the diagnosis is confirmed after careful evaluation, following exclusion of alternate diagnosis
including hypoplastic myelodysplastic syndromes. Emerging use of molecular cyto‐
genomics is helpful in delineating immune mediated AA from inherited bone marrow failures
(IBMF). Camitta criteria is used to assess disease severity, which along with age and
availability of human leucocyte antigen compatible donor are determinants for therapeutic …