[HTML][HTML] H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients

K Schleich, J Kase, JR Dörr, S Trescher… - Nature …, 2020 - nature.com
… -myc transgenic lymphomas – with … patients with diffuse large B-cell lymphoma (DLBCL).
Importantly, we interrogate the murine lymphoma capacity to senesce and its epigenetic control

H3K9 trimethylation controls oncogenic signaling and the malignant state in mantle cell lymphoma

A Hajmirza - 2017 - theses.hal.science
H3K9me3-mediated regulation of long-… epigenetic regulation of gene transcription is the
genome spatiotemporal organization within the nucleus. Around one third of human and mouse

H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells

V Ramponi, L Richart, M Kovatcheva… - Cancer …, 2024 - aacrjournals.org
… between 1C metabolism and the epigenetic regulation of transcription, we … H3K9me3-mediated
epigenetic regulation of senescence in mice predicts outcome of lymphoma patients

Ageing microenvironment mediates lymphocyte carcinogenesis and lymphoma drug resistance: From mechanisms to clinical therapy

Y Zhang, J Chu, Q Hou, S Qian… - International …, 2024 - spandidos-publications.com
… In this chapter, the biomarkers of senescent lymphoma cells … in mice helped successfully
predict the prognosis of patients … , epigenetic regulation inducing TIS, immune regulation

Adaptive T-cell immunity controls senescence-prone MyD88-or CARD11-mutant B-cell lymphomas

M Reimann, J Schrezenmeier… - Blood, The Journal …, 2021 - ashpublications.org
… Here, we functionally investigate primary mouse lymphomas that formed in recipient mice
of Eµ-myc transgenic hematopoietic stem cells stably transduced with naturally occurring NF-…

T Cells Spatially Regulate B Cell Receptor Signaling in Lymphomas through H3K9me3 Modifications

LS Britto, D Balasubramani, S Desai… - Advanced …, 2024 - Wiley Online Library
… and suggest lymphoma cells have … cancer cells but has not achieved expected potential in
clinical trials [47, 95-97]. Despite evidence of direct cooperation between H3K9me3-mediated

[HTML][HTML] Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming

J Torrano, A Al Emran, H Hammerlindl, H Schaider - Clinical epigenetics, 2019 - Springer
… between epigenetic dysregulation and senescence in cancer … states of reversibility, epigenetic
regulation, dedifferentiation and … timely H3K9me3-mediated repression of fgf8—to control

[HTML][HTML] The Roles of H3K9me3 Writers, Readers, and Erasers in Cancer Immunotherapy

U Oleksiewicz, M Kuciak, A Jaworska… - International Journal of …, 2024 - mdpi.com
… Similarly, direct H3K9me3-mediated immune escape was … as an important biomarker for
predicting metastasis. Using the … The silencing required sequential epigenetic regulation by …

[HTML][HTML] Histone modifications and their targeting in lymphoid malignancies

M Fernández-Serrano, R Winkler, JC Santos… - International journal of …, 2021 - mdpi.com
… In conclusion, mechanisms of epigenetic regulation are … Myc mice for predicting chemotherapy
treatment outcomes of … caused cellular senescence and arrested lymphoma growth in …

Clinical Expression, Prognosis and Immune Infiltration of SUV39H1 in Diffuse Large B-cell Lymphoma

Y Zhang, Q Wen, YX Lei, JJ Ge, XS Kong, WH Wang… - 2022 - researchsquare.com
Epigenetic regulation plays a crucial part in the oncogenesis … SUV39H1 transgenic mouse
models of senescence condition. It … mouse model to predict prognosis of DLBCL patients [17] , …