Hantaviruses are important zoonotic pathogens of public health importance that are found
on all continents except Antarctica and are associated with hemorrhagic fever with renal
syndrome (HFRS) in the Old World and hantavirus pulmonary syndrome (HPS) in the New
World. Despite the significant disease burden they cause, no FDA-approved specific
therapeutics or vaccines exist against these lethal viruses. The lack of available
interventions is largely due to an incomplete understanding of hantavirus pathogenesis and …