This work aims to validate in control hardware in the loop (CHIL) simulations new voltage profile control strategies in distribution systems with different levels of photovoltaic penetration. The proposed control is implemented through intelligent inverters with control functions that act through voltage sensitivity. The Volt–VAr (V–V) and Volt–Watt (V–W) functions act in the local voltage control being implemented in a complementary way. The simulations are performed in real time, using the real-time digital simulator. Residential load profiles, solar irradiance and temperature curves are discretized hourly over a daily period, with the intention of making the emulation more realistic. Voltage source converters were implemented in RSCAD software. The contribution of this article points to the performance of the Volt–Watt (V–W) control function in single-stage inverters, which allows the maximum generation of instantaneous active power, acting directly on the maximum power point tracking algorithm, this strategy being validated by the CHIL simulation. The results show that the Volt–VAr and Volt–Watt control functions, acting at different levels of photovoltaic penetration, were effective in preventing the voltage profiles from violating the critical level imposed by the regulatory standard. Leading to the conclusion that its implementation directly in photovoltaic inverters entails a low cost and a complementary solution for the new challenges of electrical systems.