Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia

E Bonifacio, L Yu, AK Williams… - The Journal of …, 2010 - academic.oup.com
Background/Rationale: Autoantibodies to islet antigen-2 (IA-2A) and glutamic acid
decarboxylase (GADA) are markers for diagnosis, screening, and measuring outcomes in
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) consortia studies.
A harmonization program was established to increase comparability of results within and
among these studies. Methods: Large volumes of six working calibrators were prepared from
pooled sera with GADA 4.8–493 World Health Organization (WHO) units/ml and IA-2A 2 …

[PDF][PDF] Harmonization of Glutamic Acid Decarboxylase and Islet Antigen-2

B Akolkar, K Adler, AG Ziegler, PW Mueller, DA Schatz… - measurements, 2010 - teddy.lu.se
Background/Rationale: Autoantibodies to islet antigen-2 (IA-2A) and glutamic acid
decarboxylase (GADA) are markers for diagnosis, screening, and measuring outcomes in
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) consortia studies.
A harmonization program was established to increase comparability of results within and
among these studies. Methods: Large volumes of six working calibrators were prepared from
pooled sera with GADA 4.8–493 World Health Organization (WHO) units/ml and IA-2A 2 …
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