… Heparan sulfate (HS) fragments belong to the class of danger/damage-… HS induces apoptosis
or necroptosis in murine cardiomyocytes. By using a novel Medical-In silico approach that …

… in cardiomyocytes, cardiomyocyte loss through necroptosis serves a … pneumoniae mouse
model in which necroptosis inhibition … In vitro experiments have confirmed that heparan sulfate …

… Medical in silico experiments and data analyses: EZ, PV, JZ, GD, AS, LM, AH, and GA. EZ
wrote the manuscript. Correction of the manuscript: EZ, PV, LM, CT, GM, GD, T-PS, and AS. …

… One of the main causes of death in hospitals worldwide is sepsis [1]. In the United States, …
by exposing cardiomyocytes to HS. In these experiments, HL-1 cells, murine cardiomyocytes, …

… induced cytokines or inflammatory mediators, we investigated the effects of tumor necrosis
factor-α (TNF-α) and burn plasma on a murine … provide a therapeutic approach for treatment of …

… We investigated the potential induction of apoptosis by eRNA released from … in murine
cardiomyocytes challenged with serum of septic patients, as a reverse translational approach. …

… of cell death that differs from necrosis in many aspects. One of … traumatic injury causes
cardiomyocyte apoptosis, mice were … To validate our method and to obtain a positive control, three …

… Heparan sulfate induces necroptosis in murine cardiomyocytes: a medical-in silico approach
… mitochondrial dysfunction in murine cardiomyocytes. Shock 44 (6), 569–577 (2015) 12. …

… as tumor necrosis factor α (TNFα) and interleukin-6 (IL-6) [9,10]. These cytokines, in turn, …
that eRNA induced significantly increased caspase-3 activation in murine cardiomyocytes (HL-…