… Its clinical importance is based on its strong association with venous and arterial
thrombosis and thromboembolism (heparin-induced thrombocytopenia with associated
thrombosis, HITT). HIT is caused by the development of an IgG antibody that recognizes
multimolecular complexes of platelet factor 4 (PF4) and heparin. … The authors describe
the case of a patient who developed HIT II with severe thrombocytopenia and the need for
platelet transfusion while on extracorporeal membrane oxygenation. … Bioline heparin-coated …