secondary metabolites as a result of their high impact of biological significance. The present
review described the literature reports of pentacyclic steroidal pyrimidines as a type of
heterocyclic steroids. The main sections included the synthesis of the investigated steroids
fused at rings-A or B or D of steroid skeleton, synthesis of binary or linked-type pyrimidines,
pyrimidine oxides, macromolecules and mono-or di-or tri-peptides linked-steroidal …