Hibiscus sabdariffa (Malvaceae) is a plant that is widely recognised for its antihypertensive
properties; however the constituent (s) responsible for this biological activity are presently
unknown. The aim of this study was to identify the potential compounds that are responsible
for the vasorelaxant activity of H. sabdariffa. Thereafter, the mechanisms involved in
producing the vasorelaxation were investigated. The plant was extracted consecutively with
hexane, ethyl acetate and methanol. The methanolic extract was subjected to bioassay …