[HTML][HTML] High D-dimer levels are associated with poor prognosis in cancer patients
haematologica, 2012•ncbi.nlm.nih.gov
Background Systemic activation of hemostasis is frequently observed in cancer patients,
even in the absence of thrombosis. Moreover, this activation has been implicated in tumor
progression, angiogenesis and metastatic spread. Increased levels of D-dimer, which is a
degradation product of cross-linked fibrin, indicate a global activation of hemostasis and
fibrinolysis.
even in the absence of thrombosis. Moreover, this activation has been implicated in tumor
progression, angiogenesis and metastatic spread. Increased levels of D-dimer, which is a
degradation product of cross-linked fibrin, indicate a global activation of hemostasis and
fibrinolysis.
Abstract
Background
Systemic activation of hemostasis is frequently observed in cancer patients, even in the absence of thrombosis. Moreover, this activation has been implicated in tumor progression, angiogenesis and metastatic spread. Increased levels of D-dimer, which is a degradation product of cross-linked fibrin, indicate a global activation of hemostasis and fibrinolysis.
ncbi.nlm.nih.gov
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