[PDF][PDF] High protein feeding induces de novo lipogenesis in healthy humans: a randomised 3-way crossover study
BACKGROUND. Dietary changes have led to a growing prevalence of Type 2 diabetes and
non-alcoholic fatty liver disease. A hallmark of both disorders is hepatic lipid accumulation,
derived in part from increased de novo lipogenesis. Despite high protein diets being popular
for weight loss to tackle these metabolic disorders, the effect of dietary protein on de novo
lipogenesis is poorly studied. We aimed to characterise the effect of dietary protein on de
novo lipid synthesis. METHODS. Herein, we use a 3-way crossover interventional study in …
non-alcoholic fatty liver disease. A hallmark of both disorders is hepatic lipid accumulation,
derived in part from increased de novo lipogenesis. Despite high protein diets being popular
for weight loss to tackle these metabolic disorders, the effect of dietary protein on de novo
lipogenesis is poorly studied. We aimed to characterise the effect of dietary protein on de
novo lipid synthesis. METHODS. Herein, we use a 3-way crossover interventional study in …
High protein feeding induces de novo lipogenesis in healthy humans: a randomised 3-way crossover study
J Griffin - 2019 - repository.cam.ac.uk
BACKGROUND. Dietary changes have led to a growing prevalence of Type 2 diabetes and
non-alcoholic fatty liver disease. A hallmark of both disorders is hepatic lipid accumulation,
derived in part from increased de novo lipogenesis. Despite high protein diets being popular
for weight loss to tackle these metabolic disorders, the effect of dietary protein on de novo
lipogenesis is poorly studied. We aimed to characterise the effect of dietary protein on de
novo lipid synthesis. METHODS. Herein, we use a 3-way crossover interventional study in …
non-alcoholic fatty liver disease. A hallmark of both disorders is hepatic lipid accumulation,
derived in part from increased de novo lipogenesis. Despite high protein diets being popular
for weight loss to tackle these metabolic disorders, the effect of dietary protein on de novo
lipogenesis is poorly studied. We aimed to characterise the effect of dietary protein on de
novo lipid synthesis. METHODS. Herein, we use a 3-way crossover interventional study in …
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